Ways to use both Helix LT and Focusrite 18i8 with Windows 11/Reaper – Helix

If/when you just want to record your guitar and perhaps an external keyboard or something similar I suggest you use the Helix LT as your audio interface. If/when you need more simultaneous inputs for recording then use the Focusrite as your audio interface and feed the LT analog outputs into it if desired.

Using the LT and its ASIO driver will allow you to record both the dry (unprocessed) and wet (processed) guitar signals simultaneously into Reaper. You can then easily apply plugins to the dry signal.